OpenVigil - open analysis tools for pharmacovigilance data

OpenVigil2_logoOpenVigil 1 and 2 are software packages to analyse pharmacovigilance data. There are several national and international databases of so called spontaneous adverse event reports, e.g., the U.S. american FDA Adverse Event Reporting System (AERS). Currently, analyses of FDA AERS (LAERS & FAERS) pharmacovigilance data are available. Analyses include disproportionality analyses like the Proportional Reporting Ratio (PRR, a measurement of disproportionality). Results can be viewed, sorted and filtered in the webbrowser or saved via CSV for further analyses in statistical software packages. For registered users, direct SQL database access enables advanced queries. OpenVigil aims at integrating FDA AERS and other pharmacolovigilance sources to pharmacoepidemiological data like prescription data.

There are live installations of both versions of OpenVigil available at Kiel university:

OpenVigil 2: http://www.is.informatik.uni-kiel.de:8503/OpenVigil/search/
(currently requires prior registration, please email us!)

OpenVigil 1: http://www.uni-kiel.de/pharmacology/pvt/openvigil.php
(development version at: http://www.uni-kiel.de/pharmacology/pvt/openvigil-current.php)

OpenVigil 1 is useful for validating results on raw FDA data. OpenVigil 2 is the successor of OpenVigil 1 and uses cleansed FDA AERS data. For scientific research, do not use OpenVigil 1 but only version 2!

You can download OpenVigil 1 (and soon OpenVigil 2) at sourceforge: http://sourceforge.net/projects/openvigil/

The project is maintained by Dr. R. Böhm, Institute of Experimental and Clinical Pharmacology, UKSH Kiel, <ruwen.boehm@pharmakologie.uni-kiel.de> and Prof. H.J. Klein, Institut für Informatik, Christian Albrechts University, Kiel, <hjk@is.informatik.uni-kiel.de>